Category: Blog

Preclinical α-FORMULATION™ Screen Introduction Preclinical formulation development plays a crucial role in pharmaceutical research, laying the foundation for successful drug discovery and clinical progression. Getting

Overcoming Challenges in HPAPI Analysis with Miniaturization Rapid Insights Highly potent active pharmaceutical ingredients (HPAPIs) play a pivotal role in modern drug development, especially in

Mitigating Salt Disproportionation Risks Rapid Insights Salt formation is a well-established strategy for increasing the solubility of ionizable drug candidates; however, the possible conversion of

Jumpstarting Formulation Development Rapid Insights Many formulators we speak with rank time pressure as the primary challenge in their programs. The main barriers often cited

The Data Package You Wish You Had but Don’t Have Time to Collect Rapid Insights An impurity formed during a chemical reaction ultimately needs to

Unleashing Bioavailability: A Synergistic Approach for the Race Against Disproportionation Rapid Insights In our latest joint white paper, we explore a breakthrough strategy to improve

The Critical Role of Solubility in Saving Time and Cost in the Development of Antibody-Drug Conjugates (ADCs) Rapid Insights Antibody-Drug Conjugates (ADCs) combine the specificity

What is ‘True Solubility’? Rapid Insights While the so-called shake-flask method is considered the industry-standard for measuring accurate solubility, there actually exists no standardized protocol.

Solubility in Chemical Synthesis Process Scaling Rapid Insights The costs and timelines for production are tied to the complexity of the chemistry and the resources

Formulate First Time Right Rapid Insights A recent conversation with an industry veteran highlighted that pharmaceutical R&D costs can increase more than 15-fold and timelines