Early determination of the actual solubility and pKa values is essential in drug discovery to understand the absorption behaviour of an API and to drive the formulation of the product. Choose the best development route for your API with less then 1mg of sample, using the SPA™ Method.
All FREE Whitepapers are available to download today:
SPA™ Technology Whitepaper
Chemistry Agnostic Whitepaper
UPDATED! Comparison SPA™ Assay vs Shake Flask Whitepaper
SPA™ Assisted Modelling Whitepaper.
Solubility and pKa Combined!
Thanks to the unique way the SPA™ Assay works, less than 1mg of sample will give 10 solubility data points and the pKa profile of your sample.
pKa information is generated alongside SPA™ Solubility Data, a powerful insight into the developability of your sample.
• USP or custom buffers ranging from pH 1.0 up to pH 14.0
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Results are fully reported to the client normally within 10 days of the sample arriving in Helsinki, faster turnarounds are available for time-critical projects.
SPA™ solubility is measured from less than 100 μg of solid sample
SPA™ Dissolution Rate is measured from less than 100 μg of solid sample
Polarized Light Microscopy Service, determine if your sample is crystaline or amorphous