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Polarized Light Microscopy (PLM) is a critical analytical tool in the characterization of drug powders, vital for understanding their microstructural properties and behaviour.
Analyzing the shape and size of drug powder particles, impacting dissolution rates and bioavailability.
Differentiating between various crystalline forms of a drug, essential for efficacy and stability.
Inspecting drug powders for uniformity, purity, and the presence of any foreign particles using optical microscopy techniques.
Studying the powder's physical properties to optimize manufacturing and processing.
Sample Preparation:
Careful preparation of drug powder samples to ensure representative and homogenous analysis.
Polarization Techniques:
Employing polarized light to enhance the visualization of powder particles’ microscopic features.
Microstructural Examination:
Detailed observation of the powder’s physical characteristics, such as shape, size, and arrangement.
High-Quality Imaging:
Capturing precise images for thorough analysis of powder quality and consistency.
State-of-the-Art Equipment: Utilization of the latest PLM technology for precise and reliable results.
Professional Expertise: Our team offers specialized knowledge in solid-state science and small molecule characterization.
Customized Services: Tailored studies to suit various needs, including research, quality control, and regulatory compliance.
Comprehensive Data Reporting: In-depth analysis and detailed reporting for actionable insights.
All FREE Whitepapers are available to download today:
SPA™ Technology Whitepaper
Chemistry Agnostic Whitepaper
UPDATED! Comparison SPA™ Assay vs Shake Flask Whitepaper
SPA™ Assisted Modelling Whitepaper.
Traditional light microscopes utilize non-polarized white light, which is visible to the human eye, whereas polarized light microscopy employs polarizing filters to utilize polarized light.
Polarized light microscopy (PLM) is utilized to ascertain the crystallinity of a sample. An amorphous sample will not display birefringence when observed under polarized light, whereas a crystalline sample will exhibit this property.
This technique enables the determination of whether a crystal is optically uniaxial or biaxial and whether it exhibits optical positivity or negativity.
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03-06 September 2024, Parsippany, NJ
Academy of Pharmaceutical SciencesPharmSci2024
04-06 September, University of Huddersfield, UK
26-27 September, Crowne Plaza Princeton, NJ