Menu
Differential Scanning Calorimetry (DSC) is a key analytical method that measures heat changes in a material as a function of temperature. It is particularly useful for small molecule characterization.
Analyzing different crystalline forms affecting bioavailability and stability.
Establishing critical temperatures for formulation and storage.
Determining crystalline vs. amorphous content, influencing dissolution rates and stability.
Establishing critical temperatures for formulation and storage.
Sample Preparation:
Accurate weighing and sealing of the sample in a specialized pan.
Temperature Control: Application of a precise temperature program, including heating and cooling.
Heat Flow Analysis:
Measurement of heat flow differences between the sample and a reference.
Data Interpretation:
Extraction of thermal properties such as transition temperatures and enthalpies from the thermogram.
State-of-the-Art Equipment: Utilization of the latest DSC technology for precise and reliable results.
Professional Expertise: Our team offers specialized knowledge in solid-state science and small molecule characterization.
Customized Services: Tailored studies to suit various needs, including research, quality control, and regulatory compliance.
Comprehensive Data Reporting: In-depth analysis and detailed reporting for actionable insights.
All FREE Whitepapers are available to download today:
SPA™ Technology Whitepaper
Chemistry Agnostic Whitepaper
UPDATED! Comparison SPA™ Assay vs Shake Flask Whitepaper
SPA™ Assisted Modelling Whitepaper.
Differential Scanning Calorimetry (DSC) measures how a sample’s heat flow differs from a reference material as both are heated or cooled. This technique, using symmetric pans with separate heaters and thermocouples, tracks temperature-induced changes like melting or reactions. By analyzing the resulting heat flow curve, DSC reveals crucial thermal properties such as melting points, glass transitions, and reaction kinetics. Widely used across material science, pharmaceuticals, and food industries, DSC aids in formulation, quality control, and understanding material stability.
Thermogravimetric analysis (TGA) observes alterations in a sample’s mass as it undergoes heating or cooling, while differential scanning calorimetry (DSC) gauges the amount of energy absorbed or released by a sample throughout temperature variations.
Yes DSC analysis is a destructive test.
Modulated differential scanning calorimetry (MDSC) enhances conventional DSC by assessing both the total heat flow and its heat capacity component, deriving the kinetic component from their disparity. This capability to deconstruct intricate transitions into distinct constituents enhances the interpretation of data.
Viikinkaari 4
00790 Helsinki
FINLAND
1 Broadway
Cambridge MA 01242
United States
03-06 September 2024, Parsippany, NJ
Academy of Pharmaceutical SciencesPharmSci2024
04-06 September, University of Huddersfield, UK
26-27 September, Crowne Plaza Princeton, NJ