The Solubility Company is pleased to announce the launch of its SPA® laboratory in the United States, located in Quakertown, Pennsylvania. This strategic move marks a significant milestone for The Solubility Company enhancing the ability to serve a growing client base across North America while enhancing the service offerings.
Key features of the new laboratory include:
Location Advantage: Situated in Quakertown, Pennsylvania, the laboratory’s proximity to major East Coast Pharma hubs in the U.S. facilitates swift shipping and receipt of samples, streamlining the process for clients by reducing paperwork and customs delays.
Unparalleled Access to Early Data: Innovative Solubility and Dissolution Rate Measurement utilizing the revolutionary Single Particle Analysis (SPA®) method to accurately measure solubility, dissolution rate, intrinsic dissolution rate, and pKa values for Active Pharmaceutical Ingredients (APIs) with minimal material consumption (less than 100 µg per measurement).
With only a milligram of material clients get access to:
★ Early insights into the solubility profile of New Chemical Entities (NCEs), guiding the selection process for potential drug candidates.
★ Guidance for pre-clinical and clinical formulation scientists by measuring the solubility in aqueous and non-aqueous vehicles to determine the success of liquid (oral and parenteral) and solid (crystalline and amorphous) dosage forms.
★ Support for process chemists to develop crystallization processes and deliver quality material by conducting organic solubility screens over the range of -20 °C to 90 °C.
Advanced Capabilities: Adding on advanced solid form screening and solid-state characterization capabilities, clients gain access to state-of-the-art equipment for Scanning Electron Microscopy, Differential Scanning Calorimetry, Thermogravimetric Analysis, Dynamic Vapor Sorption, X-ray Powder Diffraction, and Polarized Light Microscopy.
Comprehensive Drug Development Services: From early-stage discovery to late-stage development, The Solubility Company offers a full spectrum of solubility and solid-state measurement services tailored to each phase of drug development, ensuring precision, efficiency, and innovation at every step.
Co-locating at Microsize LLC gives The Solubility Company clients access to further downstream GMP particle-engineering capabilities to help bringing their molecules quickly to the clinic.